5-Metoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester - Names and Identifiers
Name | 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester
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Synonyms | 5-Methoxy-6-azaindole-2-ethylcarboxylate Ethyl 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylate 5-Metoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylicacid ethyl ester 5-Methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester
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CAS | 3469-63-4
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5-Metoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester - Physico-chemical Properties
Molecular Formula | C11H12N2O3
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Molar Mass | 220.22 |
Density | 1.269 |
Melting Point | 103-106℃ |
Boling Point | 384.4±37.0 °C(Predicted) |
pKa | 12.38±0.40(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
5-Metoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester - Introduction
1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid-, 5-methoxy-, ethyl ester is an organic compound with the chemical formula C13H13NO3.
Nature:
-Appearance: Colorless to light yellow crystalline or solid
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and dimethyl sulfoxide, insoluble in water
-Melting point: about 80-85 ℃
-Molecular weight: 235.25g/mol
Use:
- 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester is an important organic synthesis intermediate, which is used as a synthetic raw material for drugs in the pharmaceutical field.
-It is also used in the synthesis of other organic compounds in chemical research, such as the preparation of hydrophobic active molecules and organic photovoltaic materials.
Preparation Method:
- 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester has various preparation methods, among which the commonly used method is through acid-catalyzed esterification. The specific step is to react 5-methoxy-1H-pyrrolo [2,3-C] pyridine-2-carboxylic acid with ethanol under appropriate conditions to generate ethyl acetate.
-The generated ethyl acetate can be extracted and separated and purified to obtain pure 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester product.
Safety Information:
- 1H-Pyrrolo[2,3-c]pyridine-2-carboxylicacid, 5-methoxy-, ethyl ester should be used and stored to avoid contact with skin and inhalation, and avoid long-term or large-scale exposure.
-Wear appropriate protective equipment such as lab gloves and goggles during operation.
-During use, maintain good ventilation conditions and avoid fire and flame.
-In case of accidental contact or inhalation, rinse thoroughly with water immediately and seek medical help.
Last Update:2024-04-09 15:17:56